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ea0081rc11.7 | Rapid Communications 11: Thyroid 2 | ECE2022

Altered expression profiles of miR-22-5p and miR-142-3p display Hashimoto´s disease and are associated with thyroid antibodies

Trummer Olivia , Foszl Ines , Schweighofer Natascha , Arifi Edi , Haudum Christoph , Reintar Sharmaine , Pilz Stefan , Theiler-Schwetz Verena , Trummer Christian , Zirlik Andreas , Schmidt Albrecht , Colantonio Caterina , Kolesnik Ewald , Verheyen Nicolas , Pieber Thomas , Obermayer-Pietsch Barbara

Background: Hashimotos thyroiditis (HT), the most prevalent autoimmune disorder of the thyroid (AITD) is characterized by the presence of circulating autoantibodies, induced by a not fully understood dysregulation of the immune system. MicroRNAs (miRNAs) are small noncoding RNAs, which can play a pivotal role in immune functions and the development of autoimmunity. The aim of the present investigation was to evaluate whether a panel of nine selected miRNAs differs in ser...

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Endocrine Abstracts

Altered expression profiles of miR-22-5p and miR-142-3p display Hashimoto´s disease and are associated with thyroid antibodies

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